Indications for pda closure in adults

How does indomethacin close PDA? What is PDA ligation? When does the ductus arteriosus close? We present two patients who were first diagnosed with PDA during adulthood.

The first case represents a more severe form of PDA , where the need for closure of the PDA is obvious.

In the second case the sequelae of the PDA are less. The indications for closure of patent ductus with small shunts, including those that are tiny and incidentally discovered (“silent”), are less certain, particularly in older adults. Endarteritis of clinically silent PDA has been reported. Somewhat conflicting on the safety of percutaneous PDA closure. Yan C, Zhao S, Jiang S, et al.

Transcatheter closure of patent ductus arteriosus with severe pulmonary arterial hypertension in adults. Zhang DZ, Zhu XY, Lv B, et al.

Trial occlusion to assess the risk of persistent pulmonary arterial hypertension after closure of a large patent ductus arteriosus in adolescents and adults with elevated pulmonary artery. As pulmonary pressures drop after delivery and systemic pressures increase, PDA leads to a persistent left to right shunting of blood from the high pressure aorta to the lower pressure pulmonary artery. Most children can have the PDA closed by inserting catheters (long thin tubes) into the blood vessels in the leg to reach the heart and the PDA , and a coil or other device can be inserted through the catheters into the PDA like a plug. The figure below on the left shows one example of how a catheterization is used to close the ductus. If surgery is neede an incision is made in the left side.

Indications for interv. Outcomes after PDA Closure. With rare exceptions, the presence of a patent ductus arteriosus ( PDA ) is an indication for surgical closure. Clearly, attention must be paid to the existence of other congenital heart lesions. Article (PDF Available) in Netherlands heart journal: monthly journal of the Netherlands Society of Cardiology and.

Objectives We sought to review our experience with surgical ventricular septal defect (VSD) closure in adults. The pulmonary artery carries blood from the heart’s right lower chamber (ventricle) to the lungs, where it is loaded up with oxygen. From the lungs, the blood returns to the heart’s left ventricle and is pumped out through the aorta to the body. PDA of which (1procedures) were performed percutaneously.

Based on this series of adult patients who underwent transcatheter PDA closure for indications ranging from dyspnea to LV dilatation, transcatheter PDA closure appears to be safe and effective. No long-term procedural complications were encountered.

Furthermore, no significant residual shunt remained with respect to all closed defects. Patients also noted marked symptomatic improvement with. There are types of medication to effectively stimulate the closure of the duct responsible for PDA. These are indomethacin and a special form of ibuprofen.

A similar proportion of infants had patent ductus arteriosus ( PDA ) closure following first and second courses of ibuprofen, regardless of gestation, suggesting that a second course of ibuprofen may be effective in closing a patent ductus arteriosus ( PDA ), obviating the need for surgery. Schneider Moore, J. The indications for ASD closure are based on the type of defect and the devices available to treat the defect. At the current time, there are two devices that have been approved for device closure by the US Food and Drug Administration.

Patent Ductus Arteriosus Circulation.